Pollen Food Allergy Syndrome

If you suffer from hay fever and you’ve experienced an itchy mouth or scratchy throat after eating certain raw fruits or vegetables, and some tree nuts, you may have symptoms of Pollen Food Allergy Syndrome, also called Oral Allergy Syndrome.

Overview

Pollen FoodAllergies are inappropriate or exaggerated reactions of the immune system to substances that, in the majority of people, cause no symptoms. Symptoms of the allergic diseases may be caused by exposure of the skin to a chemical, of the respiratory system to particles of dust or pollen (or other substances), or of the stomach and intestines to a particular food." rel="tooltip">AllergySyndrome (PFAS), also known as oral allergy syndrome, is caused by cross-reacting allergens found in both pollen and raw fruits, vegetables, or some tree nuts. TheThe immune system is a collection of cells and proteins that works to protect the body from potentially harmful, infectious microorganisms (microscopic life-forms), such as bacteria, viruses and fungi. The immune system plays a role in the control of cancer and other diseases, but also is the culprit in the phenomena of allergies, hypersensitivity and the rejection of transplanted organs, tissues and medical implants." rel="tooltip">immune systemrecognizes the pollen and similar proteins in the food and directs an allergic response to it. People affected by PFAS can usually eat the same fruits or vegetables in cooked form because the proteins are distorted during the heating process, and the immune system no longer recognizes the food.

PFAS typically does not appear in young children. The arrival is more common in older children, teens and young adults who have been eating the fruits or vegetables in question for years without any problems. Young children under the age of 3 do not usually develop allergicRhinitis is an inflammation of the mucous membrane that lines the nose, often due to an allergy to pollen, dust or other airborne substances. Seasonal allergic rhinitis also is known as "hay fever," a disorder which causes sneezing, itching, a runny nose and nasal congestion." rel="tooltip">rhinitis(hay fever) until after they are toddlers. Hay fever is associated with reactions to the pollens that cross-react with the foods Those with PFAS typically have allergy to birch, ragweed, or grass pollens.

Speak to an Allergist.

If you’re always getting an itchy mouth after eating the same raw fruit or vegetable, see an allergist for diagnosis and treatment.

Triggers

Although not everyone with a pollen allergy experiences PFAS when eating the following foods, they are commonly associated with these allergens:

  • Birch pollen: apple, almond, carrot, celery, cherry, hazelnut, kiwi, peach, pear, plum
  • Grass pollen: celery, melons, oranges, peaches, tomato
  • Ragweed pollen: banana, cucumber, melons, sunflower seeds, zucchini

Symptoms

Symptoms of PFAS include itchy mouth, scratchy throat, or swelling of the lips, mouth, tongue, and throat. Itchy ears and hives on the mouth are sometimes reported. The symptoms are usually confined to one area and do not normally progress beyond the mouth, It is rare that a patient would develop symptoms away from the mouth, oranaphylaxisfrom this, although it has been reported in a very small percentage of patients. Because the symptoms usually subside quickly once the fresh fruit or raw vegetable is swallowed or removed from the mouth, treatment is not usually necessary.

Diagnosis

pfa的诊断是由后病人的clinical history and, in some cases, conducting skin prick tests and oral food challenges with raw fruit or vegetables.

If you or your child experience a reaction beyond the mouth area after eating a fresh fruit or raw vegetable, that food could be considered a risk foranaphylaxis, a serious reaction that comes on quickly and may cause death. In one study, researchers found that PFAS progressed to systemic symptoms in nearly 9 percent of patients and to anaphylactic shock in 1.7 percent of patients. Consult with yourallergistfor more information and to determine whether you should carry anEpinephrine is a naturally occurring hormone, also called adrenaline. It is one of two chemicals (the other is norepinephrine) released by the adrenal gland. Epinephrine increases the speed and force of heart beats and thereby the work that can be done by the heart. It dilates the airways to improve breathing and narrows blood vessels in the skin and intestine so that an increased flow of blood reaches the muscles and allows them to cope with the demands of exercise. Epinephrine has been produced synthetically as a drug since 1900. It remains the drug of choice for treatment of anaphylaxis." rel="tooltip">epinephrineauto-injector to treat potential severe reactions.

Management

Avoiding the food in raw forms is the most common way to manage this. If a food cannot be eaten in cooked form, e.g., melons, you might choose to avoid eating those foods if they cause intolerable symptoms. If you experience significant throat discomfort or difficulty swallowing, or have systemic symptoms, reactions to cooked forms of the foods, or symptoms to high-risk foods such as peanut or tree nuts, your allergist may prescribe an epinephrine auto-injector.

This page was reviewed for accuracy 3/21/2019.